WHO《儿童常见疾病管理指南》（2013）、NICE《5岁以下儿童发热评估和初步管理》（2021）、意大利儿科医师联合会指南（2021）以及中国《0至5岁儿童病因不明急性发热诊断和处理若干问题循证指南》（2016）和《儿童呼吸道感染家庭用药指导专家共识》（2023）均明确指出：对乙酰氨基酚与布洛芬在退热效果和安全性方面相似[8-12]。

作者：谌谌 编辑：笛子 图源：图虫创意 参考文献（滑动查看） [1] de Oliveira, J., Mignoni, I., Vancampfort, D., Zou, L., Stubbs, B., Waclawovsky, A. J., & Schuch, F. B. (2026). Association between handgrip strength and incident depression: a meta-analysis of prospective cohort studies. Journal of psychiatric research, 196, 106–114. https://doi.org/10.1016/j.jpsychires.2026.02.023 [2] Jiang, R., Westwater, M. L., Noble, S., Rosenblatt, M., Dai, W., Qi, S., Sui, J., Calhoun, V. D., & Scheinost, D. (2022). Associations between grip strength, brain structure, and mental health in > 40,000 participants from the UK Biobank. BMC medicine, 20(1), 286. https://doi.org/10.1186/s12916-022-02490-2 [3] Novick, D., Montgomery, W. S., Aguado, J., Peng, X., Brugnoli, R., & Haro, J. M. (2015). Which somatic symptoms are associated with an unfavorable course in Chinese patients with major depressive disorder?. Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists, 7(4), 427–435. https://doi.org/10.1111/appy.12189 [4] Ma, M., Zhang, Y., Liu, Z., Lv, S., Tao, K., & Lu, Z. (2026). Neural Circuitry Remodeling in Chronic Pain and Depression Comorbidity: Toward an Emotion-Perception Integration Network Model.Brain Research Bulletin, 111784. [5] Han, C., & Pae, C. U. (2015). Pain and depression: a neurobiological perspective of their relationship. Psychiatry investigation, 12(1), 1–8. https://doi.org/10.4306/pi.2015.12.1.1 [6] Gershon, M. D. (1998). The second brain : the scientific basis of gut instinct and a groundbreaking new understanding of nervous disorders of the stomach and intestine / Michael D. Gershon. (First edition.). HarperCollinsPublishers. [7] Bertollo AG, Santos CF, Bagatini MD and Ignácio ZM (2025) Hypothalamus-pituitary-adrenal and gut-brain axes in biological interaction pathway of the depression. Front. Neurosci. 19:1541075. doi: 10.3389/fnins.2025.1541075 [8] Huang, J., Cai, Y., Su, Y., Zhang, M., Shi, Y., Zhu, N., Jin, F., Peng, D., & Fang, Y. (2021). Gastrointestinal Symptoms During Depressive Episodes in 3256 Patients with Major Depressive Disorders: Findings from the NSSD. Journal of affective disorders, 286, 27–32. https://doi.org/10.1016/j.jad.2021.02.039 [9] Nikolova, V. L., Pelton, L., Moulton, C. D., Zorzato, D., Cleare, A. J., Young, A. H., & Stone, J. M. (2022). The Prevalence and Incidence of Irritable Bowel Syndrome and Inflammatory Bowel Disease in Depression and Bipolar Disorder: A Systematic Review and Meta-Analysis. Psychosomatic medicine, 84(3), 313–324. https://doi.org/10.1097/PSY.0000000000001046 [10] Nummenmaa, L., Glerean, E., Hari, R., & Hietanen, J. K. (2014). Bodily maps of emotions. Proceedings of the National Academy of Sciences of the United States of America, 111(2), 646–651. https://doi.org/10.1073/pnas.1321664111 [11] Toynbee, M., Zygmunt, D., Levett, R., Moghaddacy, S., & Pappa, S. (2026). The prevalence of insomnia in depressed adults: a systematic review. Psychiatry research, 356, 116888. https://doi.org/10.1016/j.psychres.2025.116888 [12] Toynbee, M., Zygmunt, D., Levett, R., Moghaddacy, S., & Pappa, S. (2026). The prevalence of insomnia in depressed adults: a systematic review. Psychiatry research, 356, 116888. https://doi.org/10.1016/j.psychres.2025.116888 [13] Pariante, C. M., & Lightman, S. L. (2008). The HPA axis in major depression: classical theories and new developments. Trends in neurosciences, 31(9), 464–468. https://doi.org/10.1016/j.tins.2008.06.006 [14] Riemann D, Berger M, Voderholzer U. Sleep and depression — results from psychobiological studies: an overview. Biological Psychology. 2001;57(1-3):67-103. [15] Böttcher, E., Schreiber, L. S., Wozniak, D., Scheller, E., Schmidt, F. M., & Pelz, J. O. (2024). Impaired Modulation of the Autonomic Nervous System in Adult Patients with Major Depressive Disorder. Biomedicines, 12(6), 1268. https://doi.org/10.3390/biomedicines12061268 [16] Grover, S., Kumar, V., Chakrabarti, S., et. al (2012). Prevalence and type of functional somatic complaints in patients with first-episode depression. East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan, 22(4), 146–153. [17] Olsen, R. K., Arnfred, S. M., Randau, M., Madsen, C., Nielsen, K. D., Shaker, A. A., Masri, H., & Hovmand, O. R. (2026). A systematic review of the prevalence of fatigue in common mental disorders (mood disorders, anxiety disorders, personality disorders, and trauma and stressor related disorders). BMC psychiatry, 10.1186/s12888-026-08094-x. Advance online publication.https://doi.org/10.1186/s12888-026-08094-x 读懂身体症状背后的情绪语言，疗愈才算真正开始。